Charles Isherwood of The New York Times praised Gugino's performance, saying, "Ms. Gugino starred in Chicago's Goodman Theater production of Eugene O'Neill's Desire Under the Elms from January 17 to February 17, 2009, in the role of Abby. The following year, she played the female lead in the thriller Righteous Kill, opposite Robert De Niro and Al Pacino. Gugino appeared as Amanda, Vincent Chase's agent, in a dozen episodes of the cable television series Entourage. Gugino appeared in the May 2007 issue of Allure. That same year she appeared in the action-horror film Rise: Blood Hunter and the feature film American Gangster. In late 2006, she appeared in an Off-Broadway production of Tennessee Williams' Suddenly Last Summer opposite Blythe Danner. Gugino appeared in the Roundabout Theatre Company play After the Fall opposite Six Feet Under's Peter Krause. The following year, she appeared in the film Night at the Museum as Ben Stiller's love interest. That same year, Gugino appeared as Lucille in the feature film adaptation of Frank Miller's graphic novel Sin City. She starred in two short-lived TV series: ABC's Elmore Leonard crime drama Karen Sisco in 2003, and CBS' science fiction series Threshold in 2005. That same year she appeared as Jet Li's love interest in the martial arts action thriller The One. In 2001, she appeared as family matriarch Ingrid Cortez in the first Spy Kids film (as well as the film's two sequels in 20). Gina Simon during the 1999–2000 final season of Chicago Hope. Fox's love interest, Ashley Schaeffer, during the first season of the sitcom Spin City in 1996, Gugino starred with Nicolas Cage in Brian De Palma's Snake Eyes, and in Judas Kiss, which she also co-produced. George (later the Duchess of Trevenick) with Greg Wise and James Frain in the BBC miniseries The Buccaneers, an adaptation of Edith Wharton's last novel. She later appeared in the video to Bon Jovi's 1994 song "Always". In film, Gugino appeared in the Shelley Long film Troop Beverly Hills, and co-starred with Pauly Shore in the 1993 romantic comedy Son in Law. Career Gugino's television work during the late 1980s and early 1990s included appearances on Good Morning, Miss Bliss, Who's the Boss?, ALF, Doogie Howser, M.D., The Wonder Years and a recurring role on Falcon Crest. So I feel like I lived two childhoods." She worked as a teenage fashion model, and took acting classes at the suggestion of her aunt, former Let's Make a Deal spokesmodel Carol Merrill. She eventually came to support herself, and with her parents' support, was legally emancipated by the time she was 16. With my dad, I lived in a beautiful house with a swimming pool and a tennis court and went to Europe for the summers. She has said of her upbringing, "I lived in a tepee in Northern California and a van in Big Sur. Early life Gugino was born in Sarasota, Florida, to Carl Gugino, an orthodontist of Italian descent, and a mother of English-Irish descent described as "Bohemian." Her parents separated when she was two, after which she travelled between her father and half-brother Carl Jr.'s home in Sarasota, and her Paradise, California, home, to which her mother moved her when she was four. Gugino also starred as the lead character in the crime drama series Karen Sisco (2003), the science fiction series Threshold (2005–2006), the supernatural horror series The Haunting of Hill House (2018), and the crime drama series Jett (2019), and also appeared in The Haunting of Bly Manor (2020). Vera Gorski in Sucker Punch (2011), Emma Gaines in San Andreas (2015), and Jessie Burlingame in Gerald's Game (2017). After appearing in Troop Beverly Hills (1989) and This Boy's Life (1993), she received recognition for her starring roles as Ingrid Cortez in the Spy Kids trilogy (2001–2003), Rebecca Hutman in Night At The Museum (2006), Laurie Roberts in American Gangster (2007), Sally Jupiter in Watchmen (2009), Dr.
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